THE PROTOCADHERINS, PCDHB1 AND PCDH7, ARE REGULATED BY MECP2 IN NEURONAL CELLS AND BRAIN TISSUES: IMPLICATION FOR PATHOGENESIS OF RETT SYNDROME

The protocadherins, PCDHB1 and PCDH7, are regulated by MeCP2 in neuronal cells and brain tissues: implication for pathogenesis of Rett syndrome

Abstract Background Rett syndrome is a neurodevelopmental and autistic disease caused by mutations of Methyl-CpG-binding protein 2 (MECP2) 730 sunken lake road gene.MeCP2 protein is mainly expressed in neurons and binds to methylated gene promoters to suppress their expression, indicating that Rett syndrome is caused by the deregulation of target g

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Does Exposure to Analgesics in Utero Cause Schizophrenia?

The cause of schizophrenia, a serious mental illness characterized by hallucinations, delusions and a marked deterioration in social functioning, is an enigma that continues to perplex the scientific community.While we know that approximately 80% of the risk of developing schizophrenia is conferred by genes (1), no research group has yet located a

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Modeling Task Uncertainty for Safe Meta-Imitation Learning

To endow robots with the flexibility to perform a wide range of tasks in diverse and complex environments, learning their controller from experience data is a promising approach.In particular, some recent meta-learning methods are shown to solve novel tasks by leveraging their experience of performing other tasks during training.Although studies ar

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Tax Neutrality on International Capital Investments

The tax policies which states follow with regard to developing technology and capital investments with raising mobility due to globalism are iphone 14 price chicago need to be discussed in its legal basis.The principle of tax neutrality has the aim of being legal foundation for these policies.According to this, the neutrality principle in taxation

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Analysis of inter-country input-output table based on citation network: How to measure the competition and collaboration between industrial sectors on the global value chain.

The input-output table is comprehensive and detailed in describing the national economic system with complex economic relationships, which embodies information of supply and demand among industrial sectors.This paper aims to scale the degree of competition/collaboration on the global value chain from the perspective of econophysics.Global Industria

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